Of 428 journal papers reporting on toxicity testing of various nanoparticles reviewed in Nov 2007 on 985 nanoparticles, the “vast majority” identified adverse effects in laboratory animals or cell lines.
Posted by envirostats on Monday, November 26, 2007
“Vast majority” isn’t a statistic but the more direct quote from the abstract is this: more than 120 studies have reported on mammalian toxicity and 270 studies reported on cytotoxicity. Unfortunately, this does not say much about “adverse effects”. Now, I’m not accusing the article source, which is different from the journal source, of distorting the truth. In fact, I very much trust Environmental Defense and its staff for quality environmental research work, especially Dr Richard Denison who gave the “vast majority” quote. What I am trying to tell you is that I don’t have access to the original journal source to be able to expound upon what “vast majority” means for a more concrete statistic, despite the 120 and 270 studies cited in the abstract that did not mention anything of the reporting done, though presumably, it means there is toxicity… presumably.
At least those wanting to know more have a source to go to now.
This sort of survey is very important because nanotechnology is quickly becoming a regular part of our lives in the Western world, but the research is so far ahead of anything regulatory or acting as a check to protect the public which any government has in place or currently planning to put in place right now. See these three articles for examples:
- Andrew Maynard: Safenano Community Blog - Are we on a nanotechnology joyride? Nov 25 2007
- The Economist: A Little Risky Business (the risk in nanotechnology). Nov 22 2007
- Natasha Loder: Overmatter Blog of Leftovers from the science desk at The Economist* - The risks of nanotechnology. Nov 23 2007
* Should be an interesting blog for me to check out as I love the Economist as a source! [Envirostats author]
Abstract (of source article for headline statistic)
The physical, chemical and biological properties of various nanomaterials differ substantially - as do the potential risks they pose. We argue that nanomaterials must be categorized based on the location of the nanoscale structure in the system/material before their hazards can be assessed and propose a categorization framework that enables scientists and regulators to identify the categories of nanomaterials systematically. The framework is applied to a suggested hazard identification approach aimed at identifying causality between inherent physical and chemical properties and observed adverse effects reported in the literature. We tested the workability of the proposed procedure using nanoparticles as an illustrative case study. A database was generated noting the reported inherent physical and chemical properties of the nanoparticles tested and the main effects observed. 428 studies were noted in the database reporting on a total of 965 nanoparticles. We found that although a limited number of studies have been reported on ecotoxicity, more than 120 and 270 have been reported on mammalian toxicity and cytotoxicity, respectively. In general there was a lack of characterization of the nanoparticles studied and it was not possible to link specific properties of nanoparticles to the observed effects. Our study shows that future research strategies must have a strong focus on characterization of the nanoparticles tested.
- Hansen, Steffen Foss, Larsen, Britt H., Olsen, Stig I. and Baun, Anders, “Categorization framework to aid hazard identification of nanomaterials,” Nanotoxicology (abstract and reference information only), published online Nov 13 2007, via Environmental Defense Press Release, Nov 19 2007
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